收费全文 | 23983篇 |
免费 | 2533篇 |
国内免费 | 403篇 |
耳鼻咽喉 | 71篇 |
儿科学 | 518篇 |
妇产科学 | 497篇 |
基础医学 | 2269篇 |
口腔科学 | 123篇 |
临床医学 | 3551篇 |
内科学 | 1777篇 |
皮肤病学 | 109篇 |
神经病学 | 8503篇 |
特种医学 | 180篇 |
外科学 | 859篇 |
综合类 | 2532篇 |
现状与发展 | 2篇 |
一般理论 | 4篇 |
预防医学 | 1517篇 |
眼科学 | 59篇 |
药学 | 2098篇 |
30篇 | |
中国医学 | 1568篇 |
肿瘤学 | 652篇 |
2024年 | 49篇 |
2023年 | 511篇 |
2022年 | 478篇 |
2021年 | 1008篇 |
2020年 | 1158篇 |
2019年 | 1073篇 |
2018年 | 1029篇 |
2017年 | 1117篇 |
2016年 | 1152篇 |
2015年 | 1002篇 |
2014年 | 1549篇 |
2013年 | 2276篇 |
2012年 | 1413篇 |
2011年 | 1425篇 |
2010年 | 1260篇 |
2009年 | 1196篇 |
2008年 | 1175篇 |
2007年 | 1138篇 |
2006年 | 998篇 |
2005年 | 843篇 |
2004年 | 671篇 |
2003年 | 636篇 |
2002年 | 546篇 |
2001年 | 420篇 |
2000年 | 291篇 |
1999年 | 204篇 |
1998年 | 177篇 |
1997年 | 180篇 |
1996年 | 121篇 |
1995年 | 162篇 |
1994年 | 171篇 |
1993年 | 131篇 |
1992年 | 149篇 |
1991年 | 119篇 |
1990年 | 101篇 |
1989年 | 118篇 |
1988年 | 107篇 |
1987年 | 116篇 |
1986年 | 93篇 |
1985年 | 115篇 |
1984年 | 83篇 |
1983年 | 62篇 |
1982年 | 64篇 |
1981年 | 50篇 |
1980年 | 43篇 |
1979年 | 32篇 |
1978年 | 22篇 |
1977年 | 25篇 |
1976年 | 18篇 |
1975年 | 15篇 |
Materials and methods: Female BPD patients (N?=?35) and healthy women (N?=?39) completed an implicit association test and the NEO-FFI personality inventory.
Results: BPD patients showed higher implicit and explicit neuroticism compared to controls. The group difference for explicit neuroticism was four times larger than that for implicit neuroticism. Presence of comorbid depressive disorder was positively correlated with implicit neuroticism. The IAT neuroticism showed excellent split-half reliability for BPD patients.
Conclusions: The present data suggest that BPD patients with comorbid clinical depression but not those without clinical depression differ from healthy individuals in their implicit self-concept of neuroticism. In the associative network, BPD patients with comorbid clinical depression exhibit stronger associations of the self with neuroticism-related characteristics, such as nervousness, fearfulness, and uncertainty than healthy individuals. Regardless of depression, BPD patients show increased explicit neuroticism. Our findings provide evidence that the IAT neuroticism can be applied reliably to BPD patients. 相似文献
Objective: We examined characteristics of caregivers and stroke survivors associated with caregivers’ depressive symptoms in the early poststroke period.
Methods: We conducted a prospective, longitudinal exploratory observational study with a convenience sample of 63 caregivers of older adult (≥ 65 years) stroke survivors recruited from urban acute-care settings. We enrolled caregivers by 2 weeks poststroke (T1) and revisited them 4 weeks later (T2). Depressive symptoms were measured using the Patient Health Questionnaire-9. A separate unadjusted linear mixed model was computed to explore significant associations between each caregiver or stroke-survivor characteristic and depressive symptoms.
Results: Caregivers, on average, reported mild depressive symptoms at T1 and T2. Each of the following characteristics was independently associated with caregiver depressive symptoms over the first 6 weeks poststroke: caregiver uncertainty (p < 0.001), perceived stress (p < 0.001) but not cortisol levels (p = 0.858 on waking, p = 0.231 evening), coping (p < 0.001), social support (p = 0.006), race (p = 0.022), income (p = 0.001), time spent on care (p = 0.039), and stroke-survivor race (p = 0.033) and functional status (p = 0.003). At T2, caregiver depressive symptoms were correlated with evening cortisol level (p = 0.001).
Conclusions: Caregiver and stroke-survivor characteristics may help identify caregivers at highest risk for early depressive symptoms and guide interventions aimed at their resolution. 相似文献
Methods: 3,742 individuals with T1D age ≥50 were followed for dementia from 1/1/96-9/30/2015. Depression, dementia, and comorbidities were abstracted from electronic medical records. Cox proportional hazard models estimated the association between depression and dementia adjusting for demographics, glycosylated hemoglobin, severe dysglycemic epidsodes, stroke, heart disease, nephropathy, and end stage renal disease. The cumulative incidence of dementia by depression was estimated conditional on survival dementia-free to age 55.
Results: Five percent (N = 182) were diagnosed with dementia and 20% had baseline depression. Depression was associated with a 72% increase in dementia (fully adjusted HR = 1.72; 95% CI:1.12-2.65). The 25-year cumulative incidence of dementia was more than double for those with versus without depression (27% vs. 12%).
Conclusions: For people with T1D, depression significantly increases dementia risk. Given the pervasiveness of depression in T1D, this has major implications for successful aging in this population recently living to old age. 相似文献